VIP (Vasoactive Intestinal Peptide)
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and a member of the secretin–glucagon peptide superfamily, carrying a C-terminal amide. It has the molecular formula C147H237N43O43S, a molecular weight of approximately 3326.8 g/mol, and CAS number 40077-57-4. Its primary sequence is His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. The peptide is a recognized ligand of the class B G-protein-coupled receptors VPAC1 and VPAC2. Supplied as a white to off-white lyophilized powder, soluble in water, stored refrigerated at 2–8 °C. This product is strictly for research purposes only.
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Independent laboratory testing confirms purity and composition of this research peptide.
+ ENDO PASSEDOverview
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide belonging to the secretin–glucagon peptide superfamily. It has the molecular formula C147H237N43O43S, a molecular weight of approximately 3326.8 g/mol, and CAS number 40077-57-4. First characterized from intestinal extracts, the peptide is widely distributed across the central and peripheral nervous systems and has been studied extensively in receptor-binding biochemistry.
VIP carries a C-terminal amide and signals through the class B G-protein-coupled receptors VPAC1 and VPAC2. Its full sequence is His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. The conserved N-terminal histidine and the central helical region are the structural determinants of receptor recognition in in-vitro studies.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C147H237N43O43S
Weight: 3326.8 g/mol
CAS: 40077-57-4
Structure: 28 amino acid C-terminally amidated peptide
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Soluble in water
Purity: ≥98% (HPLC)
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
Size: 3mg, 6mg
SKU: AXIOM-VIP
Categories: Single Peptides
Tags: Research Chemical
This product is strictly for research purposes only. Not for human or animal consumption.
