5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule quinolinium derivative and a selective, substrate-competitive inhibitor of nicotinamide N-methyltransferase (NNMT). It is most commonly supplied as the iodide salt, with the molecular formula C10H11IN2, a molecular weight of approximately 286.11 g/mol, and CAS number 42464-96-0. The active cation (C10H11N2+) consists of a methylated quinolinium ring bearing a 5-amino substituent. Supplied as a yellow to off-white crystalline powder, soluble in water and DMSO, stored refrigerated at 2–8 °C. This product is strictly for research purposes only.
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+ ENDO PASSEDOverview
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule quinolinium derivative most commonly supplied as the iodide salt. The salt has the molecular formula C10H11IN2, a molecular weight of approximately 286.11 g/mol, and CAS number 42464-96-0. It is widely used in biochemical research as a selective, substrate-competitive inhibitor of nicotinamide N-methyltransferase (NNMT).
Structurally, the active cation (C10H11N2+, MW ≈ 159.21) is a methylated quinolinium ring carrying a 5-amino substituent. The compound targets the substrate-binding site of NNMT and has been characterized in in-vitro enzyme-inhibition and cell-based studies.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
This product is strictly for research purposes only. Not approved for human or animal use.
Key Characteristics
MOLECULAR PROFILE
Formula: C10H11IN2 (iodide salt)
Weight: 286.11 g/mol
CAS: 42464-96-0
Structure: Quinolinium small molecule (NNMT inhibitor)
PHYSICAL PROPERTIES
Form: Yellow to off-white crystalline powder
Solubility: Soluble in water and DMSO
Purity: ≥98% (HPLC)
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
Size: 10mg, 20mg, 50mg
SKU: AXIOM-5-AMINO-1MQ
Categories: Single Peptides
Tags: Research Chemical
This product is strictly for research purposes only. Not for human or animal consumption.
