CJC-1295
CJC-1295 (no DAC), also called Modified GRF (1-29), is a synthetic 29-amino acid peptide and modified analog of growth hormone-releasing hormone (GHRH). First synthesized in the early 2000s, it replicates the first 29 amino acids of native GHRH with four strategic substitutions at positions 2, 8, 15, and 27 that resist cleavage by dipeptidyl peptidase-IV (DPP-IV). The “no DAC” label means this version lacks the Drug Affinity Complex used in the longer-acting variant. Molecular formula: C152H252N44O42; weight: approximately 3,368 g/mol; CAS: 446036-97-1. Supplied as a lyophilized powder, soluble in water. This product is strictly for research purposes only.
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Certificate of Analysis
Independent laboratory testing confirms purity and composition of this research peptide.
+ ENDO PASSEDOverview
CJC-1295 (no DAC) is a synthetic peptide consisting of 29 amino acids, also referred to as Modified GRF (1-29) or Mod GRF. It is a truncated and modified analog of growth hormone-releasing hormone (GHRH), which is naturally a 44-amino acid peptide produced in the hypothalamus. CJC-1295 was first synthesized in the early 2000s. The “no DAC” designation indicates this version lacks the Drug Affinity Complex — a reactive chemical group used in the longer-acting variant to bind covalently to serum albumin.
The compound has the molecular formula C152H252N44O42, an approximate molecular weight of 3,368 g/mol, and a CAS number of 446036-97-1. It is supplied as a lyophilized powder that is soluble in water. Four amino acid substitutions at positions 2, 8, 15, and 27 of the native GHRH(1-29) sequence replace residues that are normally vulnerable to enzymatic cleavage by dipeptidyl peptidase-IV (DPP-IV), giving this analog greater stability in solution than the unmodified fragment.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C152H252N44O42
Weight: ~3,368 g/mol
CAS: 446036-97-1
Structure: 29 amino acids with 4 strategic substitutions
PHYSICAL PROPERTIES
Form: Lyophilized powder
Solubility: Soluble in water
Half-life: Approximately 30 minutes
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
Size: 10mg, 5mg
SKU: AXIOM-CJC-1295
Categories: Single Peptides
Tags: Research Chemical
This product is strictly for research purposes only. Not for human or animal consumption.
