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SS-31

SS-31

$85$325

SS-31 is a synthetic tetrapeptide — a chain of four amino acids with the sequence D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2′,6′-dimethyltyrosine, a modified form of tyrosine. Its molecular formula is C32H49N9O5, its molecular weight is approximately 639.8 g/mol, and its CAS number is 736992-21-5. The peptide belongs to a class of mitochondria-targeted tetrapeptides whose structure follows an alternating aromatic-cationic motif (positive charge, aromatic ring, positive charge, aromatic ring), which gives it membrane-permeable characteristics. SS-31 has a structural affinity for cardiolipin, a phospholipid found almost exclusively in the inner mitochondrial membrane. Supplied as a white to off-white lyophilized powder, it is soluble in water. This product is for research purposes only.

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Certificate of Analysis

Independent laboratory testing confirms purity and composition of this research peptide.

+ ENDO PASSED
99.99%
Purity
A1029
Batch
June 2026
Date
View Certificate →

Overview

SS-31 is a synthetic tetrapeptide — a chain of four amino acids with the sequence D-Arg-Dmt-Lys-Phe-NH2. “Dmt” stands for 2′,6′-dimethyltyrosine, a modified version of the natural amino acid tyrosine. The molecular formula is C32H49N9O5, and it has a molecular weight of approximately 639.8 g/mol. Its CAS registry number is 736992-21-5. The peptide carries a net positive charge at physiological pH due to the arginine and lysine residues.

SS-31 belongs to a class of mitochondria-targeted tetrapeptides designed with mitochondrial membrane-compatible structural features. The peptide’s small size and alternating aromatic-cationic motif (positive charge, aromatic ring, positive charge, aromatic ring) give it membrane-permeable characteristics. It has a structural affinity for cardiolipin, a phospholipid found almost exclusively in the inner mitochondrial membrane. SS-31 is supplied as a white to off-white lyophilized powder that is soluble in water.

This product is strictly for research purposes only. Not approved for human or animal use.

PubChem Reference: View compound profile on NIH PubChem

Key Characteristics

MOLECULAR PROFILE

Formula: C₃₂H₄₉N₉O₅

Weight: 639.8 g/mol

CAS: 736992-21-5

Sequence: D-Arg-Dmt-Lys-Phe-NH₂

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Water-soluble

Storage: Keep refrigerated 36‑46 °F (2‑8 °C)

Stability: Stable when properly stored

Size: 10mg, 50mg

SKU: AXIOM-SS-31

Categories: Single Peptides

Tags: Research Chemical

This product is strictly for research purposes only. Not for human or animal consumption.

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The statements on this website have not been evaluated by the U.S. Food and Drug Administration. The products and information provided by Axiom Research are not intended to diagnose, treat, cure, or prevent any disease. Axiom Research is a research chemical supplier. We are not a compounding pharmacy or compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act, nor are we an outsourcing facility as defined under Section 503B.

All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.

SS-31 — Axiom Research