Selank
Selank is a synthetic heptapeptide based on tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) found as a fragment of the immunoglobulin G heavy chain. First described in the late 1990s, it extends tuftsin with a Pro-Gly-Pro tripeptide tail to resist enzymatic breakdown. The compound has the molecular formula C33H57N11O9, a weight of 751.87 g/mol, and CAS number 129954-34-3. Also designated TP-7, it is supplied as a white to off-white lyophilized powder, readily soluble in water. The Pro-Gly-Pro extension resists cleavage by prolyl endopeptidases, giving Selank greater persistence than native tuftsin. This product is strictly for research purposes only.
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Certificate of Analysis
Independent laboratory testing confirms purity and composition of this research peptide.
+ ENDO PASSEDOverview
Selank is a synthetic heptapeptide — a chain of seven amino acids — with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It was first described in the late 1990s. Structurally, Selank is based on tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) that is a fragment of the heavy chain of immunoglobulin G (IgG). The design extended tuftsin by adding a Pro-Gly-Pro tripeptide tail — the same stabilizing extension used in Semax — to slow enzymatic degradation.
The compound has the molecular formula C33H57N11O9, a molecular weight of 751.87 g/mol, and a CAS number of 129954-34-3. It is also known by the designations TP-7 and Selanc. Selank is supplied as a white to off-white lyophilized powder that is readily soluble in water. The Pro-Gly-Pro motif resists cleavage by prolyl endopeptidases, which gives Selank greater stability in solution compared to the parent tuftsin fragment, which is rapidly degraded.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C₃₃H₅₇N₁₁O₉
Weight: 751.87 g/mol
CAS: 129954-34-3
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Readily soluble in water
Storage: Keep refrigerated 36‑46 °F (2‑8 °C); reconstituted solution at 35-46°F (2-8°C)
Also Known As: TP-7
Size: 10mg, 5mg
SKU: AXIOM-SELANK
Categories: Single Peptides
Tags: Research Chemical
This product is strictly for research purposes only. Not for human or animal consumption.
