Melanotan 2
Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide — a ring-shaped chain of seven amino acids — and an analog of alpha-melanocyte-stimulating hormone (alpha-MSH). It has the molecular formula C50H69N15O9, a molecular weight of 1024.20 g/mol, and a CAS number of 121062-08-6. Its defining structural feature is a lactam bridge, an internal bond that closes the amino acid chain into a ring, making it more compact and enzyme-resistant than linear peptides. First synthesized in the 1990s, MT-2 is classified as a non-selective melanocortin receptor agonist, meaning it is structurally compatible with multiple receptor subtypes (MC1R, MC3R, MC4R, MC5R). Supplied as a white to off-white lyophilized powder, it is soluble in water and dilute acetic acid. This product is for research purposes only.
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+ ENDO PASSEDOverview
Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide — a ring-shaped chain of seven amino acids — designed as an analog of alpha-melanocyte-stimulating hormone (alpha-MSH). Its molecular formula is C50H69N15O9, and it has a molecular weight of 1024.20 g/mol. The CAS registry number is 121062-08-6. The key structural feature that distinguishes MT-2 from its linear predecessor Melanotan 1 is a lactam bridge, an internal bond that connects two amino acids within the chain and forces the peptide into a cyclic (ring) shape. This cyclic structure makes the molecule more compact and more resistant to breakdown by enzymes.
Melanotan 2 was first synthesized in the 1990s, building on the earlier work that produced Melanotan 1. While MT-1 is selective for the MC1R receptor, MT-2’s cyclic structure gives it structural compatibility with multiple melanocortin receptor subtypes, including MC1R, MC3R, MC4R, and MC5R. This broad receptor-family classification is a direct consequence of its three-dimensional shape. The compound is classified as a non-selective melanocortin receptor agonist. It is supplied as a white to off-white lyophilized powder that is soluble in both water and dilute acetic acid.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C50H69N15O9
Weight: 1024.20 g/mol
CAS: 121062-08-6
Structure: Cyclic heptapeptide with lactam bridge
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Soluble in water and acetic acid
Selectivity: Non-selective MC1R/3R/4R/5R agonist
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
Size: 10mg, 5mg
SKU: AXIOM-MELANOTAN-2
Categories: Single Peptides
Tags: Research Chemical
This product is strictly for research purposes only. Not for human or animal consumption.
