GLP3-R
GLP3-R is a research-designated synthetic peptide classified as a triple receptor agonist — it incorporates structural motifs from the GLP-1, GIP, and glucagon receptor ligand families. Built on a modified GIP backbone with a C20 fatty diacid chain for albumin binding, it has the molecular formula C221H342N46O68, a weight of approximately 4,191.7 g/mol, and CAS number 2381089-83-2. The addition of glucagon receptor activity, achieved through specific amino acid substitutions, distinguishes it structurally from dual agonists. Supplied as a lyophilized powder, soluble in water. This product is strictly for research purposes only.
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Certificate of Analysis
Independent laboratory testing confirms purity and composition of this research peptide.
+ ENDO PASSEDOverview
GLP3-R is a research-designated synthetic peptide classified as a triple agonist — meaning it is structurally designed around three receptor-binding motifs — corresponding to the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptor families. Its structure is based on a modified GIP peptide backbone with a C20 fatty diacid lipid chain attached via a linker.
The compound has the molecular formula C221H342N46O68, a molecular weight of approximately 4,191.7 g/mol, and a CAS number of 2381089-83-2. It is supplied as a white to off-white lyophilized powder that is soluble in water. What distinguishes GLP3-R structurally from dual agonists is the addition of a glucagon receptor-complementary sequence, achieved through specific amino acid substitutions in the peptide chain. The lipid modification serves the same purpose as in other acylated peptides — it enables albumin binding, which extends the molecule’s half-life in solution.
This product is strictly for research purposes only. Not approved for human or animal use.
PubChem Reference: View compound profile on NIH PubChem
Key Characteristics
MOLECULAR PROFILE
Formula: C221H342N46O68
Weight: 4191.7 g/mol
CAS: 2381089-83-2
Targets: GLP-1, GIP, Glucagon receptors
PHYSICAL PROPERTIES
Form: Lyophilized powder (white to off-white)
Solubility: Water-soluble
Storage: Keep refrigerated 36‑46 °F (2‑8 °C)
Reconstitution: Mix with bacteriostatic water
Size: 10mg, 12mg, 20mg, 24mg, 5mg
SKU: AXIOM-RETATRUTIDE
Categories: Single Peptides
Tags: Research Chemical
This product is strictly for research purposes only. Not for human or animal consumption.
